UC San Diego’s study reveals that meth and PCP impair memory by causing neurons to switch from glutamate to GABA, a process reversible with specific treatments.

Sustained drug abuse can have many long-lasting effects, including memory loss and reduced cognitive functions, which can persist for years. Now, neurobiologists at the University of California San Diego have identified a reversible, shared mechanism in the brain by which drugs of different classes generate cognitive impairments.

Investigating mechanisms of drug-induced cognitive deficits.