ABOVE: Blackiston and his colleagues dovetailed biology and robotics to generate biobots derived from frog stem cells. These biobots can move due to cilia, small hairlike structures that cover their surfaces. Douglas Blackiston and Sam Kriegman, licensed under CC BY 4.0.
Douglas Blackiston, a developmental biologist at Tufts University, has always been fascinated by transformation. Using uncommon model organisms, from caterpillars and butterflies to tadpoles and frogs, he investigates how biology is adaptive. In one of his favorite projects, Blackiston transplanted eyes into the tails of blind tadpoles, restoring their vision in a striking display of tissue plasticity. This led him to an unusual spin-off project, where his work in biology dovetailed with robotics. In this work, Blackiston and his colleagues repurposed frog stem cells into programmable synthetic organisms to explore the design space of cells and their interactions.
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