Nov 27, 2023

Genome haplarithmisis sheds light on complex genetic landscape of miscarriages

Posted by in categories: biotech/medical, genetics

About 10–15% of pregnancies fail after conception has been recognized, amounting to 23 million losses a year. Chromosomal anomalies underlie many embryonic and fetal losses, but their exact frequency and localization to the embryo or placenta are still unclear. A new study published in Nature Medicine reports on a chromosomal analysis of over 1,700 spontaneous early miscarriages.

The most common period of pregnancy loss is before the ninth week, though many may occur earlier and pass unrecognized. While about 11% of women have at least one miscarriage, the proportion goes down with two or three, at 2% and 0.7. respectively.

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