Cells hidden in the skull may point to a way to detect, diagnose and treat inflamed brains.
A detailed look at the skull reveals that bone marrow cells there change and are recruited to the brain after injury, possibly traveling through tiny channels connecting the skull and the outer protective layer of the brain. Paired with the discovery that inflammation in the skull is disease-specific, these new findings collectively suggest the skull’s marrow could serve as a target to track and potentially treat neurological disorders involving brain inflammation, researchers report August 9 in Cell.
New observations of skull cell signals and skull tunnels suggest bone marrow there could be used to monitor neurological diseases.
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