Likewise, this dataset had 4,510 cases, 212,242 controls, with 16,380,464 SNPs for psoriasis, and 2,802 cases, 212,242 controls, with 16,380,459 SNPs for psoriasis vulgaris.
The team analyzed the aggregated statistical data using an MR approach to explore the potential causal relationship between the gut microbiome and psoriasis. SNPs with a threshold P-value of 1 × 10−5 worked as genetic instrumental variables in these MR analyses.
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