FRO is effective against acne
The disc diffusion experiment results indicated that 20 μL FRO successfully suppressed CA growth, producing distinct 13 mm inhibition zones at a concentration of 100 mg/mL. FRO significantly suppressed CA-induced increases in sebum production, thereby slowing or reversing acne onset.
FRO was found to be rich in phenolic compounds, including gallic acid, kaempferol, quercetin, and fisetin. The concentration of total phenolic compounds (TPCs) averaged 118.2 mg gallic acid equivalents (GAEs) for every gram of FRO.
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