As researchers make major advances in medical care, they are also discovering that the efficacy of these treatments can be enhanced by individualized approaches. Therefore, clinicians increasingly need methods that can both continuously monitor physiological signals and then personalize responsive delivery of therapeutics.
Implanted bioelectronic devices are playing a critical role in these treatments, but there are a number of challenges that have stalled their widespread adoption. These devices require specialized components for signal acquisition, processing, data transmission, and powering.
Up to now, achieving these capabilities in an implanted device has entailed using numerous rigid and non-biocompatible components that can lead to tissue disruption and patient discomfort. Ideally, these devices need to be biocompatible, flexible, and stable in the long term in the body. They also must be fast and sensitive enough to record rapid, low-amplitude biosignals, while still being able to transmit data for external analysis.
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