Scientists have repurposed human stomach cells into tissues that release insulin in response to rising blood sugar levels in a breakthrough that promises an effective way to manage conditions such as type 1 diabetes.
The experiment, led by researchers from Weill Cornell Medicine in the US, revealed transplants of gastric insulin-secreting (GINS) cells reversed diabetes in mice.
Pancreatic beta cells normally do the job of releasing the hormone insulin in response to elevated sugar levels in the blood. In people with diabetes, these tissues are damaged or die off, compromising their ability to move glucose into cells for fuel.
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