Feb 25, 2023

How scientists made this rat the oldest living lab rat — E5 rejuvenation?

Posted by in categories: biotech/medical, genetics, life extension, neuroscience

Talking about E5.

Rats are also useful for aging research and for cooking ratatouille. But in all seriousness, take a look at this recent headline article — “We have the oldest living female Sprague Dawley rat,” said Dr Harold Katcher, a former biology professor at the University of Maryland, now chief scientific officer at Yuvan Research, a California-based startup.

So, Rejuvenation & rats. That’s what we’re talking about today, and how this rat has apparently become the longest living rat for its species following concentrated plasma injections from young blood plasma, and what this could mean for human therapeutics, along my perspectives. But, before we get there we must go back, back to the late 1950s and early 1960…to a time when The Sheekey Science Show did not exist, but when researchers, such as Clive McKay did, and these researchers were conducting a procedure called heterochronic parabiosis.

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Conference i mentioned —

Intro — 00:00
Plasma & rejuvenation — 00:45
E5 Rat plasma experiments — 04:00
Discussion — 09:44

Patent —…3678-1
Reversing age: dual species measurement of epigenetic age with a single clock. Steve Horvath bioRxiv 2020.05.07.082917; doi:
Villeda, S., Plambeck, K., Middeldorp, J. et al. Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice. Nat Med 20659–663 (2014).
i took the video interview clips from @yuvanresearch2749

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