Jan 31, 2023

Tissue nanotransfection causes tumor regression by its effect on nanovesicle cargo that alters microenvironmental macrophage state

Posted by in category: biotech/medical

Year 2022 Nanotransfection can essentially cure cancer for pennies destroying cancer on a cellular level non-invasively not causing problems for other cells either.

Tumor cells release extracellular vesicles (EVs) containing miR-126 angiomiR cargo, which, when delivered to tumor-associated macrophages (TAMs), generate a tumorigenic TAM subset as identified by single-cell RNA sequencing (RNA-seq). Nanoscopic imaging reveals miR-126 in single EVs. Tissue nanotransfection intervention to inhibit miR-126 (TNTanti-miR-126) prevents tumor-related death and ensures tumor-free survival.

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