Nov 30, 2022

Sexual-lineage-specific DNA methylation regulates meiosis in Arabidopsis

Posted by in categories: biotech/medical, genetics, life extension

Year 2017 This is essentially the mechanism for plant immortality.

RNA-directed DNA methylation (RdDM) activity in the Arabidopsis thaliana male sexual lineage that regulates gene expression in meiocytes. Loss of sexual-lineage-specific RdDM causes mis-splicing of the MPS1 gene (also known as PRD2), thereby disrupting meiosis. Our results establish a regulatory paradigm in which de novo methylation creates a cell-lineage-specific epigenetic signature that controls gene expression and contributes to cellular function in flowering plants.

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