If you enjoyed this video, you might like my book: https://ageless.link/
I saw a Twitter thread about Bryan Johnson’s ‘Blueprint’, claiming that he’d made himself biologically younger with a highly optimised combination of diet, supplements and exercise. What could that mean? And should we all start chugging 25 pills a day to start on the Blueprint ourselves? Probably not…but the biology behind it is surprisingly interesting.
*Chapters*
00:00 A tweet goes viral.
00:44 Getting ‘biologically younger’
01:23 NAD levels.
03:09 Maximum heart rate.
04:12 Epigenetic clocks.
07:12 Step 1: the Blueprint diet.
09:23 Step 2: ALL THE SUPPLEMENTS
11:43 Step 3: track progress.
12:40 Conclusion.
*Sources and further reading*
My book, Ageless: The new science of getting older without getting old, goes into far more depth about rapamycin, metformin and epigenetic clocks, and lots more! https://ageless.link/
Max Hertan’s extremely retweeted thread on Twitter:
My thread in response:
‘Age-predicted maximal heart rate revisited’ https://www.sciencedirect.com/science/article/pii/S0735109700010548
The ‘Horvath clock’ https://genomebiology.biomedcentral.com/articles/10.1186/gb-…45;10-r115
The ‘PhenoAge’ clock https://www.aging-us.com/article/101414/text.
Bryan Johnson’s Project Blueprint website https://blueprint.bryanjohnson.co/
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