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Sep 1, 2022

A microbial supply chain for production of the anti-cancer drug vinblastine

Posted by in categories: biotech/medical, chemistry

De novo microbial biosynthesis of vindoline and catharanthine using a highly engineered yeast and in vitro chemical coupling to vinblastine is carried out, positioning yeast as a scalable platform to produce many monoterpene indole alkaloids.

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