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Jul 27, 2022

Research shows investigational drug fosters nerve repair after injury

Posted by in categories: biotech/medical, neuroscience

𝐑𝐞𝐬𝐞𝐚𝐫𝐜𝐡 𝐬𝐡𝐨𝐰𝐬 𝐢𝐧𝐯𝐞𝐬𝐭𝐢𝐠𝐚𝐭𝐢𝐨𝐧𝐚𝐥 𝐝𝐫𝐮𝐠 𝐟𝐨𝐬𝐭𝐞𝐫𝐬 𝐧𝐞𝐫𝐯𝐞 𝐫𝐞𝐩𝐚𝐢𝐫 𝐚𝐟𝐭𝐞𝐫 𝐢𝐧𝐣𝐮𝐫𝐲


Scientists from the University of Birmingham have shown that a brain-penetrating candidate drug currently in development as a cancer therapy can foster regeneration of damaged nerves after spinal trauma.

The , published today in Clinical and Translational Medicine, used cell and animal models to demonstrate that when taken orally the candidate drug, known as AZD1390, can block the response to DNA damage in and promote of damaged nerves, so restoring sensory and after .

The announcement comes weeks after the same research team showed a https://medicalxpress.com/news/2022-05-spinal-cord-injury-treatment.html">different investigational drug (AZD1236) can reduce damage after spinal cord injury, by blocking the inflammatory response. Both studies were supported by AstraZeneca’s Open Innovations Program, which shares compounds, tools, technologies and expertise with the scientific community to advance drug discovery and development…

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