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May 12, 2022

Could an Atlas of the Brain’s Genome Solve Neuropsychiatric Disorders?

Posted by in categories: biotech/medical, genetics, neuroscience

Dr. Thomas Lehner was tired of his research repeatedly hitting a wall.

A scientist at the National Institute of Mental Health, Lehner studies the genetic underpinnings of neuropsychiatric disorders. Teasing out associated genes turned out to be relatively simple. Schizophrenia, for example, is linked to small variations in some 360 genes.

The problem is identifying the ones that really matter—culprit gene variants that can be turned into predictive tests, similar to the BRCA gene for breast cancer.

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