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May 26, 2022

CCR5 is a suppressor for cortical plasticity and hippocampal learning and memory

Posted by in categories: biotech/medical, neuroscience

Repression of the G protein-coupled chemokine receptor CCR5 enhances MAPK/CREB signaling, long-term potentiation, somatosensory cortical plasticity, and learning and memory, while CCR5 over-activation by viral proteins may contribute to HIV-associated cognitive deficits.

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