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Dec 3, 2021

Karl Deisseroth: Optogenetics, Psychiatry, Emotion, Autism, Dissociation & “Projections” | #35

Posted by in categories: genetics, neuroscience

Nick talks to Stanford psychiatrist and neuroscientist Dr. Karl Deisseroth. They discuss a range of topics about the brain, including autism, depression, bipolar disorder, dissociation, and more. They also talk about optogenetics, a technique Karl co-developed which uses light to control specific neurons in the brain, allowing neuroscientists to turn circuits in the brain on and off to reveal how the brain generates perception, emotion, and behavior. They also talk about Karls’ new book, “Projections: A Story of Human Emotion.”

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About Nick Jikomes:

Nick is a neuroscientist and podcast host. He is currently Director of Science & Innovation at Leafly, the world’s largest cannabis information resource. He received a Ph.D. in Neuroscience from Harvard University and a B.S. in Genetics from the University of Wisconsin-Madison.

0:00:00 Episode Intro.
0:03:44 Karl Deisseroth Intro.
0:07:19 “Projections” Book Synopsis.
0:13:02 Language & Psychiatry.
0:18:19 Psychiatry vs. Neurology vs. Neuroscience.
0:20:57 What is Optogenetics?
0:29:46 Optogenetics Video Example.
0:38:25 Can Optogenetics Be Used in Humans?
0:44:09 Anxiety.
0:50:34 Brain Basis of Complex Behaviors.
0:58:50 Importance of Basic Research.
1:08:46 Dissociation.
1:20:02 Treatment Resistant Depression.
1:23:30 Ketamine, Psychedelics & Depression.
1:28:24 Autism.
1:36:55 Final Thoughts

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