Oct 20, 2021

Researchers design antibodies that destroy old cells, slowing down aging

Posted by in categories: biotech/medical, life extension, neuroscience

No one knows why some people age worse than others and develop diseases-such as Alzheimer’s, fibrosis, type 2 diabetes or some types of cancer-associated with this aging process. One explanation for this could be the degree of efficiency of each organism’s response to the damage sustained by its cells during its life, which eventually causes them to age. In relation to this, researchers at the Universitat Oberta de Catalunya (UOC) and the University of Leicester (United Kingdom) have developed a new method to remove old cells from tissues, thus slowing down the aging process.

Specifically, they have designed an antibody that acts as a smart bomb able to recognize specific proteins on the surface of these aged or senescent . It then attaches itself to them and releases a drug that removes them without affecting the rest, thus minimizing any potential side effects.

The results of this work, which have been published in Scientific Reports, open the door to the development of effective treatments to delay the progress of age-related diseases and even the aging process itself in the longer term, with the aim of increasing the longevity and, above all, the quality of life of people at this stage of their lives.

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