Jun 15, 2021

Inflammatory Processes Are Altered in the Brains of People With Opioid Use Disorder

Posted by in categories: biotech/medical, neuroscience

Summary: Neuroinflammation may be a key player in the pathological brain changes produced as a result of chronic opioid use. Microglia is likely responsible for the majority of the changes.

Source: boston university school of medicine.

Prevalence rates of opioid use disorder (OUD) have increased dramatically, accompanied by a surge of overdose deaths–nearly 50000 in the U.S. in 2019. While opioid dependence has been extensively studied in preclinical models, an understanding of the biological alterations that occur in the brains of people who chronically use opioids and who are diagnosed with OUD remains limited.

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