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Mar 10, 2021

Rapamycin Anti Aging — Worth The Hype?

Posted by in categories: biotech/medical, genetics, life extension

Rapamycin is the drug used to suppress the immune system after organ transplants, but in reduced doses, it appears it may have other health benefits and as such is discussed considerably in the longevity community, and taken regularly my some very famous proponents.

So I thought I would give you some background, alongside the pros and cons, to see what all the fuss is about…


Rapamycin Anti Aging.

Rapamycin is very popular in the anti aging paradigm so let’s have a look at what it is, what it offers, and what the trade offs are… because, well, it is always wise to have all the data.

If you want to know more about the hallmarks of aging I mentioned then check this out.

Links to studies mentioned.
Extension of chronological life span in yeast by decreased TOR pathway signaling.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1356109/

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2786175/

Unlike dietary restriction, rapamycin fails to extend lifespan.
https://onlinelibrary.wiley.com/doi/10.1111/acel.13302#.YCsRkk7C3I0.twitter.

Immune memory-boosting dose of rapamycin.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119820/

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