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Jan 13, 2021

Researchers identify promising model for studying human aging

Posted by in categories: biotech/medical, life extension, neuroscience

Aging research fans might like.

“In their work, Hamiliton’s team found that the Dunkin Hartley guinea pig was a good candidate for a muscle aging model due to the animal’s tendency to develop osteoarthritis (OA) at a young age.”


There are many components to aging, both mental and physical. When it comes to the infrastructure of the human body—the musculoskeletal system that includes muscles, bones, tendons and cartilage—age-associated decline is inevitable, and the rate of that decline increases the older we get. The loss of muscle function—and often muscle mass—is scientifically known as sarcopenia or dynapenia.

For adults in their 40s, sarcopenia is hardly noticeable—about 3% is lost each decade. For those aged 65 years and older, however, can become much more rapid, with an average loss of 1% muscle mass each year. More importantly, sarcopenia is also marked by a decrease in strength, impaired gait, reduced physical activity, or difficulty completing everyday tasks.

The proportion of older adults aged 65+ is projected to more than double by the year 2060, driving research into the process of musculoskeletal decline. Researchers at Colorado State University’s Columbine Health Systems Center for Healthy Aging believe they have found an that will help them better understand it and find ways to curtail the symptoms.

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