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Jun 23, 2020

Scientists produce first open source all-atom models of COVID-19 ‘spike’ protein

Posted by in categories: biotech/medical, chemistry

The virus SARS coronavirus 2 (SARS-CoV-2) is the known cause of coronavirus disease 2019 (COVID-19). The “spike” or S protein facilitates viral entry into host cells.

Now a group of researchers from Seoul National University in South Korea, University of Cambridge in UK, and Lehigh University in USA, have worked together to produce the first open-source all-atom models of a full-length S . The researchers say this is of particular importance because the S protein plays a central role in viral entry into cells, making it a main target for vaccine and antiviral drug development.

The details can be found in a paper, “Developing a Fully-glycosylated Full-length SARS-CoV-2 Spike Protein Model in a Viral Membrane” just published online in The Journal of Physical Chemistry B.

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  1. Good to see lots of development coming out for COVID19 now. I hope it ends sooner.