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Nov 19, 2019

Brent Nally interviews Dr. Michael Fossel about Telocyte and telomerase gene therapy on 11/16/2019

Posted by in categories: bitcoin, ethics, finance, life extension, media & arts, neuroscience, transhumanism

Haven’t heard from Fossel in awhile. This is long but well indexed in the notes.


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This video me, Brent Nally, interviewing Dr. Michael Fossel about Telocyte and telomerase gene therapy on November 16, 2019.

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SHOW NOTES:

0:20 Dr. Michael Fossel intro — Follow Michael on LinkedIn: https://www.linkedin.com/in/michael-fossel-4196255/ ; http://www.michaelfossel.com/
2:00 Planned January 2020 interview with Michael.
2:25 Buy Michael’s 3 books: 1) Reversing Human Aging 2) Cells Aging & Human Disease 3) The Telomerase Revolution.
4:15 https://telocyte.com/
5:07 Aging complexities
8:20 Small molecules won’t reverse human aging.
9:01 People are fixed in their incorrect beliefs about aging.
12:50 Sometimes we have to first go backwards to move forwards. My March 26, 2019 interview with Dr. Ed Park at Recharge Biomedical: https://youtube.com/watch?v=xHgfYKsH0uw&list=UUCwpkla04tVxHJUds2J2aqA&index=6
15:55 Economics of radically increasing the human healthspan.
19:01 Leonard Hayflick
21:05 The rate of telomere loss is linked to many organism’s lifespan.
22:30 Lengthening human telomeres in aging cells “resets” the cells to make them biologically younger.
24:10 Cells, Aging, and Human Disease preface.
28:20 human population if we radically increase human healthspan/lifespan.
31:20 biological vs chronological aging
32:25 telomerase activation is the best point of clinical and financial intervention to cure and prevent age related diseases.
37:30 Data generally doesn’t support the idea that making telomerase more active in humans can cause cancer. Michael beliefs this idea has been propagated by misinterpreting data.
45:02 Causation & Pathology in Alzheimer’s Disease.
46:30 standard cell aging process
49:53 What can you do to help cure human aging? understand the concepts, share this info & invest.
53:40 the FDA is excited about Telocyte’s model.
55:30 Phase 1 human FDA trial costs about $10 million but costs should drop after that.
57:50 It costs Telocyte about $4 million to initially produce the telomerase gene therapy they need to treat their first 12 patients.
58:55 Lets “elephant hunt” to find billionaire investors for Telocyte.
1:01:18 Michael discusses BioViva/Integrated Health Systems & Liz Parrish. My July 10, 2019 interview with BioViva CEO Liz Parrish: https://youtube.com/watch?v=oBFTwGPaPr4
1:02:10 My May 30, 2019 interview with Sierra Sciences CEO Dr. Bill Andrews: https://youtube.com/watch?v=Tx9yG6iTROQ
1:09:45 ethics and risks of telomerase gene therapy.
1:11:15 Unnatural selection on Netflix
1:14:30 Is reality a simulation?
1:18:10 The mind is like a parachute. It only works if it’s open. Data trumps everything always.
1:19:50 telomerase activator pills
1:24:30 Dr. Greg Fahy
1:28:40 https://lifelength.com/ & https://teloyears.com/home/
1:32:40 My July 17, 2019 interview with Dr. Aubrey de Grey https://www.youtube.com/watch?v=TquJyz7tGfk
1:38:34 Dr. Michael West
1:41:10 Inject snake venom for anti-aging? https://www.youtube.com/watch?v=8q_m-rDUNw0
1:45:15 Bill Haast https://en.wikipedia.org/wiki/Bill_Haast
1:45:50 My October 6, 2019 interview of Dr. Duncan Ross about Kimera exosomes: https://www.youtube.com/watch?v=X8eIxo3eqvQ&t=3s
1:46:15 Brent’s stem cell’s treatment and recovery playlist https://www.youtube.com/playlist?list=PLGjySL94COVQzsAauqp6lZHHzmzBQSmhH
1:51:52 Dr. Maria Blasco
1:52:45 Michael almost got $1 billion for a non-profit translational research for telomerase gene therapy from a wealthy couple in California in 1999.
1:55:45 Dr. Elizabeth Blackburn
1:57:57 Dr. Elissa Epel
2:00:09 Dr. Calvin Harley
2:02:20 Radical honesty and compassion
2:06:25 I recommend the book: Sapiens by Dr. Yuval Noah Harari
2:11:15 Michael’s fascinating experiences.
2:26:30 telomerase gene therapy economies of scale.
2:35:10 Dr. Peter Attia
2:36:50 Peter Rayson, CEO Telocyte. Curing human aging is a systems approach.
2:39:43 Forever Labs 1 year free cryogenic storage discount code ($250 value): BN801 https://foreverlabs.com
2:42:10 Dave Asprey — lack of funding for Telocyte is holding back the potential cure for Alzheimer’s.
2:44:30 Chan Zuckerberg Initiative
2:49:08 health advice
2:56:38 Viome for microbiome
3:01:04 the best current way to measure someone’s age is guessing based off how they look and behave.
3:04:51 transhumanism and ignosticism
3:08:23 Stay curious to continue learning.
3:16:28 “What important truth do very few people agree with you on?”
3:23:30 be considerate

- Intro music by: SoundSage
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