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Jul 19, 2019

‘Trojan horse’ anticancer drug disguises itself as fat

Posted by in category: biotech/medical

A stealthy new drug-delivery system disguises chemotherapeutics as fat in order to outsmart, penetrate and destroy tumors.

Thinking the drugs are tasty fats, tumors invite the drug inside. Once there, the targeted drug activates, immediately suppressing tumor growth. The drug also is lower in toxicity than current chemotherapy drugs, leading to fewer side effects.

“It’s like a Trojan horse,” Northwestern University’s Nathan Gianneschi, who led the research. “It looks like a nice little fatty acid, so the tumor’s receptors see it and invite it in. Then the drug starts getting metabolized and kills the tumor cells.”

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