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Apr 1, 2019

Depression, obesity, chronic pain could be treated by targeting the same key protein

Posted by in categories: biotech/medical, neuroscience

Major depression, obesity and chronic pain are all linked to the effects of one protein, called “FK506-binding protein 51,” or FKBP51. Until now, efforts to inhibit this target have been hampered by the difficulty of finding something specific enough to do the job and not affect similar proteins. Now a research group has developed a highly selective compound that can effectively block FKBP51 in mice, relieving chronic pain and having positive effects on diet-induced obesity and mood. The new compound also could have applications in alcoholism and brain cancer.


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  • flashgordon on April 1, 2019 11:17 am

    Let’s see here — bullies leads to depression — put the depressed on drugs and let the bullies continue doing their thing.

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