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Apr 2, 2019

Depression genes debunked: analysis dashes highly studied link

Posted by in categories: genetics, neuroscience

Research out of the University of Colorado Boulder has dashed research into a potential link between certain genes and depression. The conclusion follows an analysis of both survey and genetic data from more than half a million people, which found that 18 candidate genes and random genes were equally associated with cases of depression.

The new study, which was recently published in the American Journal of Psychiatry, looked at 18 highly-studied ‘candidate genes,’ each of which had previously been studied in association with depression a minimum of 10 times. The results were called “a little bit stunning” by study senior author Matthew Keller.

According to the study, these 18 candidate genes weren’t associated with depression more than other randomly chosen genes. Past research into the genes that had indicated a link between the two were called false positives, though the researchers caution that this doesn’t mean depression isn’t heritable.

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