A team of Japanese researchers has—for the first time—demonstrated preserving frozen animal cells without a cryoprotectant agent (CPA), a substance that can protect biological material from freezing damage. To keep cells alive, all the conventional freezing methods needed to add a CPA, which can be potentially toxic and associated with cell damage and death. Their method only relies on ultrarapid cooling—or really fast freezing—for cells and vital biological material during freezing process. A safe freezing without CPA method would not only revolutionize how important research and medical material is stored, but greatly advance any and all research methods within those fields. The study was published in Proceedings of the National Academy of Sciences (PNAS) on April 1st, 2019.
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