Mar 14, 2019

33 blood-cancer patients have dramatic clinical remission with new T-cell therapy

Posted by in categories: biotech/medical, genetics

Image of a group of killer T cells (green and red) surrounding a cancer cell (blue, center) (credit: NIH)

Chinese doctors have reported success with a new type of immunotherapy for multiple myeloma, a blood cancer: 33 out of 35 patients in a clinical trial had clinical remission within two months.

The researchers used a type of T cell called “chimeric antigen receptor (CAR) T.” In a phase I clinical trial in China, the patient’s own T cells were collected, genetically reprogrammed in a lab, and injected back into the patient. The reprogramming involved inserting an artificially designed gene into the T-cell genome, which helped the genetically reprogrammed cells find and destroy cancer cells throughout the body.

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