Jul 16, 2018

X-rays burst chemo-filled nanobubbles for targeted cancer drug delivery

Posted by in categories: biotech/medical, nanotechnology

Researchers at the Center for Nanoscale BioPhotonics (CNBP) have developed a new targeted treatment for cancer. Chemotherapy drugs are wrapped in “nano-bubbles” called liposomes, which are then injected into the desired part of the body and made to release their payload on demand, by applying X-ray radiation.

Liposomes are regularly used to protect drugs and carry them to where in the body they’re needed. Over the years, we’ve seen them used to protect insulin doses from the harsh environment of the gut long enough for it to enter the bloodstream, disarm bacteria without using antibiotics, and escort cancer-killers to tumors.

“Liposomes are already well established as an extremely effective drug-delivery system,” says Wei Deng, lead author of the study. “Made out of similar material as cell membranes, these ‘bubbles’ are relatively simple to prepare, can be filled with appropriate medications and then injected into specific parts of the body. The issue however, is in controlling the timely release of the drug from the liposome.”

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