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Apr 26, 2018

Novel antioxidant makes old blood vessels seem young again

Posted by in categories: biotech/medical, life extension

Taking the supplement, dilation of subjects’ arteries improved by 42 percent, making their blood vessels, at least by that measure, look like those of someone 15 to 20 years younger. An improvement of that magnitude, if sustained, is associated with about a 13 percent reduction in heart disease, Rossman said. The study also showed that the improvement in dilation was due to a reduction in oxidative stress.


Older adults who take a novel antioxidant that specifically targets cellular powerhouses, or mitochondria, see age-related vascular changes reverse by the equivalent of 15 to 20 years within six weeks, according to new University of Colorado Boulder research.

The study, published this week in the American Heart Association journal Hypertension, adds to a growing body of evidence suggesting pharmaceutical-grade nutritional supplements, or nutraceuticals, could play an important role in preventing heart disease-the nation’s No. 1 killer. It also resurrects the notion that oral antioxidants, which have been broadly dismissed as ineffective in recent years, could reap measurable health benefits if properly targeted, the authors say.

“This is the first clinical trial to assess the impact of a mitochondrial-specific antioxidant on vascular function in humans,” said lead author Matthew Rossman, a postdoctoral researcher in the department of integrative physiology. “It suggests that therapies like this may hold real promise for reducing the risk of age-related cardiovascular disease.”

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  • Bennie Beaver on April 26, 2018 1:33 pm

    I’m a senior who has read about all kinds of new research developments over the years, and yet, I go to my doctor, luckily only once a year, and feel like I’m still in the 1960s.

    Too little seems to have changed. Yes, blood test have improved, than they check your height, weight. check heart with an age old stethoscope, and maybe order an ultrasound check of arteries; and that is about it.The office looks essentially just like it did in the 1960s.

    When in the world will medical science get new developments on the market and in the doctors office; or directly to my mail box. When will FDA or science stop reporting breakthroughs, talking, and start doing? Maybe by the year 2525 if we’re all still alive!