To Dr. Mark Gomelsky, a professor at the University of Wyoming, genetically engineered therapeutic cells are like troops on a mission.
The first act is training. Using genetic editing tools such as CRISPR, scientists can “train” a patient’s own cells to specifically recognize and attack a variety of enemies, including rogue tumor soldiers and HIV terrorists.
Then comes the incursion. Engineered cells are surgically implanted to the target site, where they’re left to immediately carry out the mission. The problem, says Gomelsky, is adding a command center “that could coordinate their activities in real time according to the developing situation,” such as telling cells when to activate and when to stop.
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