Apr 25, 2017

Possible approach for treating Alzheimer’s

Posted by in categories: biotech/medical, life extension, neuroscience

Quercetin may be able to influence apoE and could be a potential therapeutic for Alzheimer’s disease.

The Apolipoprotein E connection

The most common type of dementia is Alzheimer’s disease and as the average life expectancy has risen in recent decades so has the occurrence of this and other neurodegenerative diseases. Aging is the primary risk factor for Alzheimer’s and researchers are searching for new ways to combat this devastating disease.

The pathology of Alzheimer’s is characterized by the formation of tau-tangles and the accumulation of amyloid-β (Aβ) which damage neurons and gradually destroy sections of the brain leading to death. The debate over which is primary, tau or amyloid is ongoing and it remains unclear which is the most important of the two, or if both are a consequence of another underlying process.

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