May 10, 2016

Gene Therapy to Treat Progressive Vision Loss

Posted by in categories: biotech/medical, health

University of Oxford scientists have developed a gene therapy that has shown promise in treating choroideremia, a rare disorder that causes progressive vision loss, mostly in males.

Doctors tested the treatment method on six patients with choroideremia by injecting numerous healthy genes into the eye to replace missing ones in the retina. The purpose of this therapy is to hinder or prevent loss of sight, according to Oxford’s announcement.

Results varied for each participant. Two patients experienced a big improvement in vision that lasted for four years, but a decline occurred in the other untreated eye. Three separate patients maintained their vision in the treated eye over four years whereas the sixth recipient who was given a lower dose succumbed to vision decline in both eyes.

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