Mar 19, 2016

Research devises a way to track RNA in living cells through CRISPR-Cas9

Posted by in categories: biotech/medical, genetics

On track to resolving defective RNA through CRISPR-Cas9.

According to a study published in journal Cell on March 17, researchers at University of California, San Diego School of Medicine, have found a way to track RNA in living cells. CRISPR-Cas9, a DNA-editing technique will be applied to target RNA in order to find cure for presently untreatable diseases such as cancer and autism.

There are many diseases that are associated with RNA behavior, which carries the genetic code from the cell’s nucleus. There was no technique found until now that could track RNA in living cells efficiently. However now, CRISPR-Cas9, which so far was only able to manipulate DNA, would now target RNA, which is also called RNA-targeted Cas9.

“Our current work focuses on tracking the movement of RNA inside the cell, but future developments could enable researchers to measure other RNA features or advance therapeutic approaches to correct disease-causing RNA behaviors”, said senior author Gene Yeo, PhD, associate professor of cellular and molecular medicine.

Read more

Comments are closed.