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Triglycerides may play an important role in brain metabolism

While glucose, or sugar, is a well-known fuel for the brain, Weill Cornell Medicine researchers have demonstrated that electrical activity in synapses—the junctions between neurons where communication occurs—can lead to the use of lipid or fat droplets as an energy source.

The study, published in Nature Metabolism, challenges “the long-standing dogma that the brain doesn’t burn fat,” said principal investigator Dr. Timothy A. Ryan, professor of biochemistry and of biochemistry in anesthesiology, and the Tri-Institutional Professor in the Department of Biochemistry at Weill Cornell Medicine.

The paper’s lead author, Dr. Mukesh Kumar, a postdoctoral associate in biochemistry at Weill Cornell Medicine who has been studying the cell biology of fat droplets, suggested that it makes sense that fat may play a role as an energy source in the brain like it does with other metabolically demanding tissues, such as muscle.

EARTh pARTy Conference

Conference at Forbes Island (San Francisco Bay) in July 2025 featuring Brewster Kahle Tim Anderson Heidi Petty:

The eARTh pARTy Conference brings together visionaries in technology, art, and culture on a unique floating island to reimagine our collective future. Over three immersive days, we’ll explore how technology can empower rather than control humanity’s creative potential.

Our world stands at a crossroads. This gathering champions a future where creators maintain ownership of their work, receive fair compensation, and preserve their digital autonomy. Together, we’ll explore what a future looks like with a distributed creative network that advocates for ethical platforms and transparent systems.

The pieces for our future already exist. We simply need the courage to reassemble them into a world where creative expression flourishes, and the impact you make becomes your most valuable asset.

Join us in launching a movement that ensures technology serves human creativity rather than exploiting it.


Building the future of creative economies: decentralized, regenerative, thriving.