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Jan 31, 2023

Artificial intelligence aids discovery of super tight-binding antibodies

Posted by in categories: biotech/medical, robotics/AI

Scientists at University of California San Diego School of Medicine have developed an artificial intelligence (AI)-based strategy for discovering high-affinity antibody drugs.

In the study, published January 28, 2023 in Nature Communications, researchers used the approach to identify a new antibody that binds a major cancer target 17-fold tighter than an existing antibody drug. The authors say the pipeline could accelerate the discovery of novel drugs against cancer and other diseases such as COVID-19 and rheumatoid arthritis.

In order to be a successful , an antibody has to bind tightly to its target. To find such antibodies, researchers typically start with a known antibody and use bacterial or to produce a series of new antibodies with variations of that sequence. These mutants are then evaluated for their ability to bind the target antigen. The subset of antibodies that work best are then subjected to another round of mutations and evaluations, and this cycle repeats until a set of tightly-binding finalists emerges.

Jan 31, 2023

Cargo airships could be big

Posted by in category: futurism

A capital-intensive, high-risk way to revolutionize global commerce.

Jan 31, 2023

Ahmedbahaaeldin/From-0-to-Research-Scientist-resources-guide: Detailed and tailored guide for undergraduate students or anybody want to dig deep into the field of AI with solid foundation

Posted by in category: robotics/AI

Detailed and tailored guide for undergraduate students or anybody want to dig deep into the field of AI with solid foundation. — GitHub

Jan 31, 2023

Claude: Brand New ChatGPT Competitor Explained

Posted by in category: robotics/AI

Love this upgrade!

In this video I discuss New ChatGPT rival Claude developed by startup Anthropic AI

Continue reading “Claude: Brand New ChatGPT Competitor Explained” »

Jan 31, 2023

Canadian team discovers power-draining flaw in most laptop and phone batteries

Posted by in categories: computing, mobile phones

The phone, tablet or laptop you’re reading this on is likely having its battery slowly drained because of a surprising and widespread manufacturing flaw, according to researchers in Halifax.

“This is something that is totally unexpected and something that probably no one thought of,” said Michael Metzger, an assistant professor at Dalhousie University.

The problem? Tiny pieces of tape that hold the battery components together are made from the wrong type of plastic.

Continue reading “Canadian team discovers power-draining flaw in most laptop and phone batteries” »

Jan 31, 2023

After a decade, CRISPR gene editing is a ‘revolution in progress.’ What does the future hold?

Posted by in categories: bioengineering, biotech/medical, food

But every once in a while, an idea is so powerful and so profound its effects are felt much faster.

That’s been the case with CRISPR gene editing, which celebrates a 10th anniversary this month. It has already had a substantial impact on laboratory science, improving precision and speeding research, and it has led to clinical trials for a handful of rare diseases and cancers.

Over the next decade, scientists predict, CRISPR will yield multiple approved medical treatments and be used to modify crops, making them more productive and resistant to disease and climate change.

Continue reading “After a decade, CRISPR gene editing is a ‘revolution in progress.’ What does the future hold?” »

Jan 31, 2023

The Believing Brain: Evolution, Neuroscience, and the Spiritual Instinct

Posted by in categories: evolution, neuroscience

God, they say, is in the details. But could God also be in our frontal lobes? Every culture from the dawn of humankind has imagined planes of existence beyond the reach of our senses, spiritual domains that shape our Earthly experiences. Why do beliefs of the fantastic hold such powerful sway over our species? Is there something in our evolutionary history that points to an answer? Does neuroscience hold the key? Straddling the gap between science and religion, Brian Greene is joined by renowned neuroscientists, anthropologists, and evolutionary biologists, to explore one of the most profound mysteries of our existence.

PARTICIPANTS: Lisa Barrett, Barbara J. King, Zoran Josipovic, Steven Pinker.

Continue reading “The Believing Brain: Evolution, Neuroscience, and the Spiritual Instinct” »

Jan 31, 2023

Dr. Paul Cisek | NeuroSymposium 2020

Posted by in category: futurism

Rethinking Behavior from an Evolutionary Perspective.

Dr. Paul Cisek.
Associate Professor, Département de neurosciences, Université de Montréal.

Jan 31, 2023

DeepMind: The Quest to Develop Artificial General Intelligence

Posted by in categories: education, Elon Musk, robotics/AI

00:00 Intro.
03:05 Demis Hassabis: Founder of DeepMind.
14:30 DeepMind: Mission and early years.
19:18 Beating the Atari games.
27:22 Elon Musk: thoughts on DeepMind.
28:42 Elon Musk: AI could destroy humanity.
30:20 AlphaGo.
36:14 AlphaZero.
38:30 MuZero.
40:56 WaveNet.
43:18 AlphaStar.
45:33 AlphaFold.
48:39 Gato, A generalist agent.
50:02 Solving *everything else*

This premium episode is a documentary-style video about the history and importance of Alphabet subsidiary, DeepMind. Demis Hassabis, founder, was a chess prodigy by the time he was 13 years old. He went on to conclude he wanted to “solve intelligence” by building artificial intelligence agents and using digital tools. The team at DeepMind has created systems that defeated the world’s best chess and Go professionals. They’ve also cracked the code on the infamous ‘protein-folding problem.’ Demis Hassabis and DeepMind are fascinating. Moreover, they’re still just getting started.

Continue reading “DeepMind: The Quest to Develop Artificial General Intelligence” »

Jan 31, 2023

Astronomers Say They Have Spotted the Universe’s First Stars

Posted by in category: alien life

A group of astronomers poring over data from the James Webb Space Telescope (JWST) has glimpsed light from ionized helium in a distant galaxy, which could indicate the presence of the universe’s very first generation of stars.

These long-sought, inaptly named “Population III” stars would have been ginormous balls of hydrogen and helium sculpted from the universe’s primordial gas. Theorists started imagining these first fireballs in the 1970s, hypothesizing that, after short lifetimes, they exploded as supernovas, forging heavier elements and spewing them into the cosmos. That star stuff later gave rise to Population II stars more abundant in heavy elements, then even richer Population I stars like our sun, as well as planets, asteroids, comets and eventually life itself.

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