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Scientists have developed Rhobo6, a light microscopy probe that reveals extracellular matrix structures in live tissues, advancing biological research and disease diagnostics.

Rhobo6 is a light microscopy probe that selectively binds to extracellular matrix glycans, increasing its fluorescence and allowing clear visualization of these structures in live tissues. This innovative tool enables researchers to study the extracellular matrix in detail without disrupting native biological processes, offering new insights into tissue biology and disease.

Before arriving at Janelia three years ago, Postdoctoral Scientist Antonio Fiore was designing and building optical instruments like microscopes and spectrometers.

Scientists have developed a way to 3D-print high-performance thermoelectric materials, promising a major leap in cooling technology. This breakthrough could cut costs, reduce waste, and improve efficiency, challenging conventional manufacturing.

UK-based Core Power has announced that it plans to mass produce a fleet of floating nuclear power plants (FNPPs) using advanced reactor design and modular shipbuilding to be anchored off the US coast in about 10 years.

Nuclear power is enjoying something of a renaissance with many countries turning to the atom to meet their energy needs. However, the bottleneck for increasing the nuclear sector isn’t with manufacturing reactors. It’s the civil engineering side of things, with most of the time and cost going to securing real estate for building the foundations and buildings for the plant as well as navigating a bewildering maze of permits, licenses, and planning permissions.

To get around this as well as speed up production, Core Power plans to use Generation 4 reactor design combined with conventional modular shipbuilding methods to crank out floating nuclear plants on an assembly line basis. To reflect this, the company is referring to this as the “Liberty program” in a call back to the famous Liberty ships of the Second World War that were built at a speed of as fast as four days for one hull.

In a phase 1 trial, patients with pancreatic ductal adenocarcinoma who were treated with surgery and bespoke neoantigen mRNA vaccines combined with anti-PD-L1 and chemotherapy exhibited marked long-lived persistence of neoantigen-specific CD8+ T cell clones, which correlated with prolonged recurrence-free survival at a 3.2-year follow-up.

Ancient texts warn of love turning into hatred, as seen in stories like Cain and Abel or “Et tu, Brute?” This talk explores the neurobiology of hatred based on the biology of love: the oxytocin system, attachment networks, and biobehavioral synchrony, which mature through mother-infant bonding and later support group solidarity and out-group hostility. Using this model, we developed Tools of Dialogue© for Israeli and Palestinian youth. After 8 sessions, participants showed reduced hostility, increased empathy, hormonal changes (lower cortisol, higher oxytocin), and lasting attitudes of compromise. Seven years later, these changes supported their peacebuilding efforts, showing how social synchrony can transform hatred into reciprocity and cooperation. Recorded on 02/14/2025. [Show ID: 40386]

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Learn more about anthropogeny on CARTA’s website:
https://carta.anthropogeny.org/

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‘Quantum Supremacy’ author Dr. Michio Kaku discusses the future of quantum computing on ‘Making Money.’ #foxbusiness #makingmoney.

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“Retrocausality” by Antonella Vannini and Ulisse Di Corpo Book Link: https://amzn.to/3X6UGhx.
“Time Loops: Precognition, Retrocausation, and the Unconscious” by Eric Wargo Book Link: https://amzn.to/4bdmWVV
“Psychology and Retrocausality: How the Future Determines Love, Memory, Evolution, Learning, Depression, Death, and What It Means to Be Human” by Mark Hatala Book Link: https://amzn.to/4k7kdBj.

The exploration of retrocausality challenges classical views of time and causality, suggesting that effects can precede their causes, influencing our understanding of quantum mechanics, consciousness, and free will. Retro causality offers potential resolutions to issues like non-locality in quantum physics by allowing communication between particles to travel backward in time, which could eliminate the need for higher dimensional configuration spaces and reconcile quantum theory with special relativity. Experimental investigations into retro-causality involve analyzing subtle effects, such as heart rate variations, and require careful methodologies to distinguish genuine retrocausal phenomena from experimental artifacts, while theoretical frameworks explore how retrocausality might address paradoxes and be compatible with concepts like time symmetry.
Thinkers in physics and philosophy are increasingly considering retrocausality as a potential framework to address foundational issues, including the measurement problem and the reconciliation of quantum mechanics with general relativity, potentially impacting our comprehension of time, causality, and the nature of reality itself. Discussions around retrocausality extend into areas like decision theory, existential risk, and the nature of consciousness, with some researchers exploring goal-oriented approaches and the potential for retrocausality to enhance artificial intelligence and our understanding of human cognition. Some notable scientists involved:
• Roger Penrose is noted for his views aligning with retrocausal concepts and his work on the science of consciousness with Stuart Hameroff.
• Yakir Aharonov is cited regarding time in quantum mechanics and weak value amplification.
• Ruth Kastner is mentioned in the context of retrocausality and the transactional interpretation of quantum mechanics.
• Hu Price’s work is at the center of the study of existential risk.
• Ken Wharton is a professor of physics and astronomy working on time-symmetric and causally neutral models of physics.
• Matthew Leifer is mentioned regarding block universe ontological models and frameworks for theories with retrocausality.
• Daniel Rohrlich is mentioned for his work on fundamental aspects of quantum mechanics and his views on retrocausality.
• Richard Feynman is mentioned in the context of interaction with the absorber as the mechanism of radiation.
• Simon Shnoll is mentioned for his work showing that the assumption of normal distribution is only mathematical, and that in life sciences and also in physics it is false.
• David Lucas is mentioned in the context of trapped-ion processing modules.

#Retrocausality #QuantumPhysics #TimeTravel #Physics #Science #Philosophy #Cosmology #Reality #Consciousness #MindBodyProblem #QuantumMechanics #Time Symmetry #Causality #Determinism #Parapsychology #time #physics #cosmology #Timelessness #PhilosophyofTime #Spacetime #GeneralRelativity #TimeCapsules #SuperstringTheory #aideepdive #InfiniteUniverse #podcast #synopsis #books #bookreview #science #quantumphysics #aiart #artificialintelligence #booktube #aigenerated #reality #videoessay #documentary

🔍 Overview: Join Robert Plomin and me as we dive deep into the fascinating world of behavioural genetics, exploring how our DNA shapes who we are, the power of environment, and whether we can rewrite our genetic destiny.

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PayPal: https://www.paypal.com/paypalme/samuehttps://www.blockchain.com/explorer/a… 🗣️ Highlights [Highlight 1]: How Does Genetics Shape Who We Are? [Highlight 2]: What Role Does the Environment Truly Play in Defining Us? [Highlight 3]: Are We Hardwired by Our DNA, or Can We Rewrite Our Destiny? 🕒 Timestamps 0:00 — Introduction 1:57 — Robert Plomin, Philosophy and Psychology 4:12 — Why Behavioural Genetics? 8:21 — Publishing Blueprint 14:51 — Heritability 30:15 — The Basics of DNA 34:34 — Genetic Variances and Binary Myths 41:21 — Labels and Certificates 45:33 — Nonshared Environments and The Nature of Nurture 1:00:51 — Self-Selecting Within Environments 1:07:04 — Group Difference and Heritability 1:13:03 — Academic Success: DNA vs. Schooling 1:21:17 — Ethical Considerations 1:27:01 — Moral Responsibility and Accountability 1:31:23 — The Future of Genetics 1:42:38 — Genetic Trajectories and Random Events 1:45:17 — The DNA Revolution 1:48:21 — Closing Remarks 📚 Episode Resources (affiliate links where possible — thanks!) Blueprint: How DNA Makes Us Who We Are by Robert Plomin: https://amzn.to/3T9htYp King’s College London: https://www.kcl.ac.uk/people/robert-p… Common Disorders are Quantitative Traits by Robert Plomin: https://pubmed.ncbi.nlm.nih.gov/19859… Gattaca (1997): https://www.imdb.com/title/tt0119177/ 🌐 Connect Linktree: https://linktr.ee/samueldevis89 Substack: https://thesocraticsessions.substack… Twitter: / samueldevis89 Facebook Page: / thesocraticsessions Instagram: / samueldevis89 Goodreads: / samuel-devis Bluesky: https://bsky.app/profile/samueldevis8… Threads: https://www.threads.net/@samueldevis89 LinkedIn Page: / thesocraticsessions 🎧 Subscribe 📺 YouTube: / @samueldevis89 Rumble: https://rumble.com/c/SamuelDevis89 Apple Podcasts: https://podcasts.apple.com/us/podcast… Spotify: https://open.spotify.com/show/6lOdYbN… Audible: https://www.audible.co.uk/pd/The-Socr… Amazon Music: https://music.amazon.co.uk/podcasts/3… Other Podcast Platforms: https://podcasters.spotify.com/pod/sh… 📷 Gear (affiliate links — thanks!) Camera (Sony A6400): https://amzn.to/46jehNn Lens (Sigma 16mm): https://amzn.to/47DfiRn Audio Interface (Focusrite Scarlett 4i4): https://amzn.to/47lJzEP Microphone Amplifier (Cloudlifter CL-1): https://amzn.to/3uou7Jq Mic (RØDE PodMic): https://amzn.to/3sJFUBE Lights (Elgato Key Light Air): https://amzn.to/3TZMgYX Colour Back Lighting (Govee LED Floor Lamp): https://amzn.to/47EGSOf Recording Software (Riverside. FM): https://www.tinyurl.com/riversidesam89 👍 Support: Like, subscribe, and share to fuel the quest for understanding. 🔔 Stay Tuned: Tap the bell for instant notifications. 📣 Join the Talk: Share your thoughts using #TheSocraticSessions. 🚀 Thanks for Tuning In! Let’s keep the conversation going. #genetics #nature #nurture #dna #heritability #genome #biology #philosophy.
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🗣️ Highlights.
[Highlight 1]: How Does Genetics Shape Who We Are?
[Highlight 2]: What Role Does the Environment Truly Play in Defining Us?
[Highlight 3]: Are We Hardwired by Our DNA, or Can We Rewrite Our Destiny?

🕒 Timestamps.