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World’s First CRISPR-Edited Spider Produces Glowing Red Silk From Its Spinneret

One of the reasons why this has never happened before is that spiders themselves are difficult organisms to work with within the laboratory. They are a diverse group, have a complex genome structure, and their cannibalistic nature means that they have to be reared individually, otherwise their cage neighbors would be gobbled up. Despite this, new developments in Parasteatoda tepidariorum have allowed this species to become a research model.

The research team looked into spider silk as the target. Spider silk is an incredibly strong and scientifically interesting substance, as it is five times stronger than a steel cable of the same weight, tear-resistant, while also being biodegradable, lightweight, and elastic.

To genetically modify this arachnophobe’s nightmare, the scientists developed an injection solution. This had a gene-editing system that also included a red fluorescent protein gene sequence. This solution was then injected into oocytes inside unfertilized female spiders, when these spiders mated with males, it resulted in the genetically modified offspring.

A Distinct New Form of Diabetes Has Been Officially Recognized

Type 5 diabetes has just been recognised as a distinct form of diabetes by the International Diabetes Federation. Despite the name, there are more than a dozen different types of diabetes. The classification isn’t quite as tidy as the numbering suggests.

Here’s a clear guide to the different types, including some that you may not have heard of, along with information about what causes them and how they are treated.

Type 1 diabetes is caused by the body’s immune system mistakenly attacking the insulin-producing cells in the pancreas. This autoimmune reaction can occur at any age, from infancy through to old age.

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