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The breakthrough engineering technology, outlined in a new study published today in Nature, dramatically advances research of vascular diseases like diabetes, identifying a key pathway to potentially prevent changes to blood vessels — a major cause of death and morbidity among those with diabetes.

An organoid is a three-dimensional structure grown from stem cells that mimics an organ and can be used to study aspects of that organ in a petri dish.

“Being able to build human blood vessels as organoids from stem cells is a game changer,” said the study’s senior author Josef Penninger, the Canada 150 Research Chair in Functional Genetics, director of the Life Sciences Institute at UBC and founding director of the Institute for Molecular Biotechnology of the Austrian Academy of Sciences (IMBA).

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LEAF writer Nicola Bagalà recounts meeting an old lady on the street and considers what might have happened in a world free from age-related diseases.


I would like to share a story about an encounter I had a couple of years back, when I was nearing the end of my university studies. At the time, I lived in a student apartment pretty much on the outskirts of Helsinki, Finland. Like most of Finland, this area is beautiful and brimming with green everywhere in the summer, but at the end of March— which is when the story takes place—it still looks like a barren, icy desert, and during a late evening like the one on which I had my encounter, it can be very cold and dark.

That evening, my girlfriend and I were coming back from the nearby supermarket, carrying two or three heavy bags full of groceries and looking forward to being home. We were talking about something I can’t recall when we passed right next to another person whose figure I could not make out very well. I had a feeling that it was a woman, but that’s all I could tell. As we walked away from her, I thought I could hear a voice calling—maybe it was her, but I told myself that she was probably talking on the phone or something. I heard her calling again, at which point I turned around to check if she was actually trying to catch our attention.

I was right—she was a woman. More specifically, an old Finnish lady, looking quite lost and tired. What follows is an account of the conversation I had with her—my girlfriend can’t really speak Finnish. I had actually written this down somewhere not too long after it had happened, but I could not remember the conversation line by line, and I had to improvise a little to fill in the blanks here and there as I translated it from Finnish. It is as accurate as I can possibly make it.

Childhood’s End


Dr. Twyman developed the idea of social futurism which can be characterized as the idea of using technology to solve social problems. Dr. Twyman has tried two variations to drive interest in the community as well as some political efforts external to that. The most recent incarnation of this was an ARG (alternate reality game). Whether you thought his approaches to Zero State and Social Futurism were good or not, the idea of Social Futurism is something we need more people to talk about.

While the details to me are unimportant in most things the central idea IS important. With Social Futurism it evolves out of the same moral and ethical model that includes a deep respect and needs to help those around us, something I think more of us and should include as part of our lives and the message we share with others through our actions and the example we set.

With the changes on the various Zero State forums, I would like to invite anyone thinking about Social Futurism and related ideas to comment.

Watch it here: https://www.youtube.com/watch?v=10dFgrjdfqY

I posed a wide array of questions for inventor, futurist, and Singularitarian Dr. Ray Kurzweil on September 21, 2018, at RAAD Fest 2018 in San Diego, California. Topics discussed include advances in robotics and the potential for household robots, artificial intelligence and overcoming the pitfalls of AI bias, the importance of philosophy, culture, and politics in ensuring that humankind realizes the best possible future, how emerging technologies can protect privacy and verify the truthfulness of information being analyzed by algorithms, as well as insights that can assist in the attainment of longevity and the preservation of good health – including a brief foray into how Ray Kurzweil overcame his Type 2 Diabetes.

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