Lifeboat Foundation

Sought after guest speaker, Aubrey de Grey, has appeared on numerous popular programs including CBS 60 Minutes, BBC, TED and The Colbert Report to name just a few. Today, he joins The Future Tech Podcast, to share his vision on how we can improve the aging process through enhancing the human body’s capability of rejuvenation through cell immortality and pluripotency to human aging and age-related disease.

The. Vice President of New Technology and Discovery at AgeX Therapeutics, Aubrey de Grey, Ph.D., is also the Chief Science Officer of SENS Research Foundation, a California-based 501©(3) biomedical research charity that performs, and funds research devoted to battling the progression of aging.

In this fascinating discussion, Aubrey explains some of the obstacles that need to be overcome, including issues involving age-related tissue damage and stem cell decline which contribute to accelerating the aging process. He also discusses what AgeX is doing in stem cell research and in regenerative medicine that will improve not only the longevity of life, but also the quality and health of individuals throughout the aging process. He also touches on what he sees could be the future in the science of aging and treatments being worked on by the rejuvenation research community.

Continue reading “Aubrey De Grey – PhD. and Vice President of New Technology Discovery at Agex Therapeutics – The Age Old Question of How Can We Combat Aging?” »

Commercial, residential, and industrial buildings use a lot of water. It’s hard for them to conserve water when there are so many people and processes relying on the liquid. It’s even worse for industrial organizations where water use is constant.

According to the U.S. Department of Energy (DOE), commercial buildings use about 88 percent of all drinkable water in the U.S. Facility managers who understand the need to conserve this water and use their resources to do so could significantly decrease water use throughout the world.

As things evolve, so will the future of water conservation. It will be about using technology, science, and more in the name of water-saving features. It will also save companies time and money.

Continue reading “How Buildings of the Future Will Conserve Water” »

A diagrammatic explanation of how machine consciousness might be feasible.

About 20 years ago I gave my first talk on how to achieve consciousness in machines, at a World Future Society conference, and went on to discuss how we would co-evolve with machines. I’ve lectured on machine consciousness hundreds of times but never produced any clear slides that explain my ideas properly. I thought it was about time I did. My belief is that today’s deep neural networks using feed-forward processing with back propagation training can not become conscious. No digital algorithmic neural network can, even though they can certainly produce extremely good levels of artificial intelligence. By contrast, nature also uses neurons but does produce conscious machines such as humans easily. I think the key difference is not just that nature uses analog adaptive neural nets rather than digital processing (as I believe Hans Moravec first insighted, a view that I readily accepted) but also that nature uses large groups of these analog neurons that incorporate feedback loops that act both as a sort of short term memory and provide time to sense the sensing process as it happens, a mechanism that can explain consciousness. That feedback is critically important in the emergence of consciousness IMHO. I believe that if the neural network AI people stop barking up the barren back-prop tree and start climbing the feedback tree, we could have conscious machines in no time, but Moravec is still probably right that these need to be analog to enable true real-time processing as opposed to simulation of that.

I may be talking nonsense of course, but here are my thoughts, finally explained as simply and clearly as I can. These slides illustrate only the simplest forms of consciousness. Obviously our brains are highly complex and evolved many higher level architectures, control systems, complex senses and communication, but I think the basic foundations of biomimetic machine consciousness can be achieved as follows:

Continue reading “Biomimetic insights for machine consciousness” »

By Julianna Photopoulos

A plasma patch could soon be used to dress wounds. Plasma is a state of matter, like a solid or gas, and can kill bacteria including those that are resistant to antibiotics. Normally plasmas form at high temperatures, but a new patch can create cold plasmas that may be ideal for use on the body.

The patch is developed by German company Coldplasmatech and produces a plasma by sending high energy electrons through the air between the patch and skin. This rips some of the electrons off molecules …

Continue reading “Bizarre state of matter to treat wounds instead of antibiotics” »

What would it be?

New research on brain ageing and mitochondria from Salk Institute.

Thanks to a new technique, researchers from the Salk Institute’s Gage laboratory have shown that impaired energy production might be a reason why human brains are susceptible to age-related diseases in the first place [1].

In particular, Salk scientists observed that induced neurons (iNs) obtained from fibroblasts of older individuals had dysfunctional mitochondria and therefore decreased energy levels compared to younger neurons. Out-of-shape mitochondria have previously been implicated in degenerative brain diseases, such as Alzheimer’s and Parkinson’s, and this finding might help reveal more about the connection between these diseases and this particular hallmark of aging.

Continue reading “Mitochondrial dysfunction in aged brain cells” »

Newts are the only four-legged vertebrates that can regenerate their body parts, even as adults. When a newt loses a limb, a mass of cells called a blastema is generated at the stump, from which a new, fully functional limb is eventually regenerated. Can this remarkable ability be explained by genes shared by vertebrates, including humans, or by unique genes that the newt may have evolved?

In a study published in Scientific Reports, researchers at several Japanese universities, including the University of Tsukuba, and the University of Dayton, report the discovery of a novel gene, Newtic1, from the blastema of an adult newt. This gene is expressed in a subset of red blood cells and may contribute to limb regeneration in adult newts. Red blood cells, or erythrocytes, function to deliver oxygen around an animal’s body. Unlike the other cells in the mammalian body, the erythrocytes lack nuclei, allowing them to carry more oxygen and squeeze into fine blood vessels. In the newt and most other non-mammalian species, however, these cells contain a nucleus. Other than oxygen delivery, the function of these nucleated cells is unknown. This study provides, for the first time, an insight into the roles of these nucleated cells.

In the study, the researchers constructed a database of all the protein-coding genes from the Japanese fire-bellied newt that had been reported in the Japan newt research community. This database contained DNA sequence information of genes from 19 different tissues, including different regenerating organs and limb blastemas. To identify genes related to limb regeneration, they used statistical analyses to look for genes whose expression was increased in association with the formation of the limb blastema. From 694,138 sequences, they found 105,464 expressed in the limb blastema. Further screening of these sequences resulted in the identification of a single gene which was named Newtic1. Its existence in newt tissues was confirmed using both DNA- and protein-based methods. Similar genes exist in axolotl and another newt species, but not in any other species.

A shortage of antibiotics is causing doctors to prescribe incorrect antibiotics for certain infections. That, in turn, is allowing antibiotic resistant organisms to develop defenses and some of those may no longer be treatable with antibiotics.

Kelsey-Seybold doctor Shane Magee says there are lots of drug shortages.

Continue reading “The Antibiotic Resistance Crisis is worsening” »

http://www.thepathmag.com/can-you-actually-hack-your-dna-to-slow-down-aging/

Many technologies / interventions progressing down the development pathways in the coming years — but there are a lot of free, common sense adjustments you can make today: