Toggle light / dark theme

Autism affects at least 2% of children in the United States—an estimated 1 in 59. This is challenging for both the patients and their parents or caregivers. What’s worse is that today there is no medical treatment for autism. That is in large part because we still don’t fully understand how autism develops and alters normal brain function.

One of the main reasons it is hard to decipher the processes that cause the disease is that it is highly variable. So how do we understand how autism changes the ?

Using a new technology called single-nucleus RNA sequencing, we analyzed the chemistry inside specific brain cells from both and those with autism and identified dramatic differences that may cause this disease. These autism-specific differences could provide valuable new targets for drug development.

Read more

Researchers have pinpointed a previously unknown source of volcanoes in the extreme depths of Earth — in the transition zone between the upper and lower mantle.

Until now, we thought we had a handle on the ways in which volcanoes form, welling up from the molten regions in the upper mantle beneath our planet’s crust, but the new discovery takes things much farther down.

In the Bermuda islands, which sit atop an extinct volcanic seamount, geologists have found the first direct evidence that material from the transition zone, between 400 and 650 kilometres (250 and 400 miles) below Earth’s surface, can bubble up and be spewed out of volcanoes.

Read more