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Feb 19, 2019

Slowing the Aging Process

Posted by in categories: biotech/medical, genetics, life extension, neuroscience

It’s inevitable in life, but aging isn’t really something people look forward to. Researchers have been seeking ways to reduce the impact of aging, not only because of vanity but also because as we age, there is a greater risk of certain serious health conditions like cancer, heart disease and neurodegenerative conditions like Alzheimer’s disease. Salk Institute scientists have now used CRISPR/Cas9, the gene-editing tool, to slow down aging. The work, reported in Nature Medicine, showed accelerated aging can be slowed in mice modeling a rare genetic disorder called Hutchinson-Gilford progeria syndrome.

“Aging is a complex process in which cells start to lose their functionality, so it is critical for us to find effective ways to study the molecular drivers of aging,” said the senior author of the report Juan Carlos Izpisua Belmonte, a professor in Salk’s Gene Expression Laboratory. “Progeria is an ideal aging model because it allows us to devise an intervention, refine it and test it again quickly.”

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Feb 19, 2019

Scientists create new map of brain’s immune system

Posted by in categories: biotech/medical, neuroscience

“We were able to show that there is only a single type of microglia in the brain that exist in multiple flavours,” says project head Prof. Dr. Marco Prinz, medical director of the Institute of Neuropathology at the Medical Center — University of Freiburg. “These immune cells are very versatile all-rounders, not specialists, as has been the textbook opinion up to now,” sums up Prof. Prinz.


A team of researchers under the direction of the Medical Center — University of Freiburg has created an entirely new map of the brain’s own immune system in humans and mice. The scientists succeeded in demonstrating for the first time ever that the phagocytes in the brain, the so-called microglia, all have the same core signature but adopt in different ways depending on their function. It was previously assumed that these are different types of microglia. The discovery, made by means of a new, high-resolution method for analyzing single cells, is important for the understanding of brain diseases. Furthermore, the researchers from Freiburg, Göttingen, Berlin, Bochum, Essen, and Ghent (Belgium) demonstrated in detail how the human immune system in the brain changes in the course of multiple sclerosis (MS), which is significant for future therapeutic approaches. The study was published on 14. February 2019 in the journal Nature.

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Feb 19, 2019

This Electric Chewing Gum Never Runs out of Flavor

Posted by in category: futurism

Caveat: it’s only flavors are “bitter” and “salty”.

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Feb 19, 2019

The effects of collagen hydrolysat on symptoms of chronic fibromyalgia and temporomandibular joint pain

Posted by in category: futurism

Cranio. 2000 Apr;18:135–41.

Olson GB, Savage S, Olson J.

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Feb 19, 2019

The Engine Powering the Future of Civilian Spaceflight Enters the Collections

Posted by in categories: futurism, space travel

Eight-year-old George Madden is wandering the “Moving Beyond Earth” gallery of the Smithsonian’s National Air and Space Museum on a blustery day in February. Clad in an orange spacesuit, he is examining the artifacts—the main engine from the Space Shuttle, flight suits, a rotating chair from a 1992 Spacelab mission—and lingering near a display about space travel. He gazes up at words printed in large white text on the wall: “When I grow up, I want to be an astronaut.”

His father, 52-year-old Michael Madden, will soon make history as one of the first 1,000 people to travel to space. Madden is a paid customer of Virgin Galactic, one of six “future astronauts” in the crowd who will be among the first wave of passengers to be carried into space by SpaceShipTwo when the company begins its commercial flights, maybe as soon as before the end of the year. Madden and his son, along with other space aficionados, are in the museum for a donation ceremony. Sir Richard Branson, founder of the Virgin Group, and Enrico Palermo, president of the Spaceship Company, are turning over the hybrid engine that powered Virgin Galactic’s SpaceShipTwo, VSS Unity, on its first space flight on December 13, 2018.

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Feb 19, 2019

Neutron Stars: Nature’s Weirdest Form of Matter

Posted by in category: futurism

The insides of neutron stars—the densest form of matter in the universe—have long been a mystery, but it is one that scientists are starting to crack.

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Feb 19, 2019

Elon Musk: Tesla will have all its self-driving car features by the end of the year

Posted by in categories: Elon Musk, robotics/AI, transportation

Tesla will have the technology to pick up passengers and drive them to destinations by the end of the year, said CEO Elon Musk said on a podcast with an investor.

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Feb 19, 2019

Episode 34: Paul Bloom on Empathy, Rationality, Morality, and Cruelty

Posted by in category: entertainment

Something about political sports hooligans not caring about the truth, etc wink

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Feb 19, 2019

Gene therapy first to ‘halt’ most common cause of blindness

Posted by in category: biotech/medical

A woman from Oxford has been treated with gene therapy in a world first, in a bid to stop sight loss.

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Feb 19, 2019

Experimental Anti-Aging Treatment That Kills Old Cells Has Passed First Human Trial

Posted by in categories: biotech/medical, life extension

Not all damaged cells die. Some stick around as senescent cells, unable to divide but still able to produce chemical signals — and they could play a major role in the battle against aging.

“It is thought that these cells and the substances they produce are involved in the process of aging,” longevity researcher Nicolas Musi from the University of Texas at Austin told MIT Technology Review.

“The idea is that removing these cells may be beneficial to promote healthy aging and also to prevent diseases of aging.”

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