Lifeboat Foundation

Imagine one drug that can target and kill malignant cells for some patients with many types of cancer. A new drug called Vitrakvi (larotrectinib), now approved by the U.S. Food and Drug Administration, shows promise of doing just that for both adults and children with a variety of sometimes rare cancers that share one specific genetic mutation.

The mutation, called a TRK fusion, occurs when one of three NTRK genes becomes mistakenly connected to an unrelated gene and ignites uncontrolled growth. By solely targeting this mutation, the drug is designed to turn off growth signaling with a minimum of other toxicities.

According to the drug manufacturer, Loxo Oncology, this specific mutation can occur in a small subset of various adult and pediatric solid tumors ranging from cancers of the appendix, bile ducts, breast, lung, pancreas and thyroid to melanoma, GIST and various sarcomas.

Continue reading “FDA Approves Drug That Targets Key Genetic Driver of Cancer” »

A number of different things have to happen for a child to develop leukemia.

A massive, previously unexplored cave discovered by accident in Canada has been named “Sarlacc’s Pit,” after the multi-tentacled alien beast that first made an appearance in Star Wars: Return of the Jedi.

Officials from Canada’s Ministry of Environment and Climate Change first came across the huge cavern in Wells Gray Provincial Park in British Columbia while conducting a caribou count by helicopter in March.

Continue reading “Massive Cave Discovered in Canada, Named After ‘Star Wars’ Beast” »

Inspired by the insulation on a humble electrical cable, researchers have found that tiny ceramic particles can make plastic-backed cladding fire-safe.

How do you make a light-weight cladding material that doesn’t catch fire? It’s a question the building industry globally is wrestling with in the wake of the 2017 Grenfell Tower blaze in London that cost the lives of 72 people.

But according to new research, the answer is under your desk in the plastic insulation around the electrical cable powering your computer.

The promise of quantum computing brings with it some mind-blowing potential, but it also carries a new set of risks, scientists are warning.

Specifically, the enormous power of the tech could be used to crack the best cyber security we currently have in place.

A new report on the “progress and prospects” of quantum computing put together by the National Academies of Sciences, Engineering, and Medicine (NASEM) in the US says that work should start now on putting together algorithms to beat the bad guys.

Continue reading “We Need to Prepare For Quantum Attacks Now, Top US Scientists Warn” »

BepiColombo has fired its ion drives in preparation for Mercury orbital injection over the next seven years.

The Salt American foulbrood is an infectious disease that devastates honeybee hives. Scientists say they’ve created a vaccine for it, despite a big hurdle: Bees don’t have antibodies.

A 68-year-old Seattle woman who died after contracting a rare brain-eating amoeba used regular tap water to rinse her sinuses, according to new research.

As noted in a new International Journal of Infectious Diseases case study, the infection was initially misdiagnosed as a brain tumor. During surgery to remove the suspected tumor, the lead neurosurgeon, Charles Cobbs from Seattle’s Swedish Medical Center, was taken aback by the extent of the brain damage. So he extracted a sample for further testing.

As on Earth, so in space. A four-satellite mission that is studying magnetic reconnection—the breaking apart and explosive reconnection of the magnetic field lines in plasma that occurs throughout the universe—has found key aspects of the process in space to be strikingly similar to those found in experiments at the U.S. Department of Energy’s (DOE) Princeton Plasma Physics Laboratory (PPPL). The similarities show how the studies complement each other: The laboratory captures important global features of reconnection and the spacecraft documents local key properties as they occur.

The observations made by the Magnetospheric Multiscale Satellite (MMS) mission, which NASA launched in 2015 to study reconnection in the magnetic field that surrounds the Earth, correspond quite well with past and present laboratory findings of the Magnetic Reconnection Experiment (MRX) at PPPL. Previous MRX research uncovered the process by which rapid reconnection occurs and identified the amount of magnetic energy that is converted to particle energy during the process, which gives rise to northern lights, solar flares and geomagnetic storms that can disrupt cell phone service, black out power grids and damage orbiting satellites.