Researchers have discovered that problems with the brain’s waste-clearing system—the glymphatic system—may significantly raise the risk of developing dementia.
Memory loss may not simply be a symptom of getting older. New research from Virginia Tech shows that it’s tied to specific molecular changes in the brain and that adjusting those processes can improve memory.
In two complementary studies, Timothy Jarome, associate professor in the College of Agriculture and Life Sciences’ School of Animal Sciences, and his graduate students used gene-editing tools to target those age-related changes to improve memory performance in older subjects. The work was conducted on rats, a standard model for studying how memory changes with age.
“Memory loss affects more than a third of people over 70, and it’s a major risk factor for Alzheimer’s disease,” said Jarome, who also holds an appointment in the School of Neuroscience. “This work shows that memory decline is linked to specific molecular changes that can be targeted and studied. If we can understand what’s driving it at the molecular level, we can start to understand what goes wrong in dementia and eventually use that knowledge to guide new approaches to treatment.”
Many young ADHD patients are medicated as soon as they’re diagnosed, possibly because the behavioral therapy they need isn’t available, a Stanford Medicine-led study found.
The discovery of ancient water in a planet-forming disk reveals that some of the water found in comets—and maybe even Earth—is older than the disk’s star itself, offering breakthrough insights into the history of water in our solar system.
Astronomers using the Atacama Large Millimeter/submillimeter Array (ALMA) have made a first-ever detection of doubly deuterated water (D₂O, or “heavy water”) in a planet-forming disk around V883 Ori, a young star. This means that the water in this disk, and by extension the water in comets that form here, predates the birth of the star itself, having journeyed through space from ancient molecular clouds long before this solar system formed.
The research is published in the journal Nature Astronomy.
As an alternative to single-use plastic wrap and paper cup coatings, researchers in Langmuir report a way to waterproof materials using edible fungus. Along with fibers made from wood, the fungus produced a layer that blocks water, oil and grease absorption. In a proof-of-concept study, the impervious film grew on common materials such as paper, denim, polyester felt and thin wood, revealing its potential to replace plastic coatings with sustainable, natural materials.
“Our hope is that by providing more ways to potentially reduce our reliance on single-use plastics, we can help lessen the waste that ends up in landfills and the ocean; nature offers elegant, sustainable solutions to help us get there,” says Caitlin Howell, the corresponding author of the study from the University of Maine.
Fungi are more than their mushroom caps; underground they form an extensive, interwoven network of feathery filaments called mycelium. Recently, researchers have been inventing water-resistant materials made from these fibrous networks, including leather-like, electrically conductive gauze and spun yarn, because the surface of mycelium naturally repels water.