In this Review, Simpson et al. summarize the emergent understanding of molecular subtypes of small cell lung cancer (SCLC). They discuss how intratumour heterogeneity and dynamic tumour plasticity may challenge the success of immune and molecular subtype-targeted therapies and argue that combination therapies, monitored by serial liquid biopsy-based biomarkers, will be needed to improve the outcomes of patients with SCLC.
The term resistant hypertension has been variably applied to patients with high blood pressure (BP) since at least the 1960s.1 Specific definitions have evolved over time to align with advances in treatment and BP goals. In 2018, the American Heart Association updated its definition of resistant…
PDF version: Notes on Ultrasound Physics – by Logan Thrasher Collins Fundamentals of ultrasound waves Sound waves such as those in ultrasound are longitudinal waves where particles oscillate …
Introducing Codex: a cloud-based software engineering agent that can work on many tasks in parallel, powered by codex-1. With Codex, developers can simultaneously deploy multiple agents to independently handle coding tasks such as writing features, answering questions about your codebase, fixing bugs, and proposing pull requests for review.
Depending on the type of artificial blood that is made, various raw materials are used. Hemoglobin-based products can use either isolated hemoglobin or synthetically produced hemoglobin.
To produce hemoglobin synthetically, manufacturers use compounds known as amino acids. These are chemicals that plants and animals use to create the proteins that are essential for life. There are 20 naturally occurring amino acids that may be used to produce hemoglobin. All of the amino acid molecules share certain chemical characteristics. They are made up of an amino group, a carboxyl group, and a side chain. The nature of the side chain differentiates the various amino acids. Hemoglobin synthesis also requires a specific type of bacteria and all of the materials needed to incubate it. This includes warm water, molasses, glucose, acetic acid, alcohols, urea, and liquid ammonia.
For other types of hemoglobin-based artificial blood products, the hemoglobin is isolated from human blood. It is typically obtained from donated blood that has expired before it is used. Other sources of hemoglobin come from spent animal blood. This hemoglobin is slightly different from human hemoglobin and must be modified before being used.
ASILAB is excited to introduce Asinoid – the world’s first true artificial superintelligence built on the architecture of the human brain. Designed to think, learn, and evolve autonomously like a living organism.
Learn more on our website: http://asilab.com.
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A new gene editor takes advantage of CRISPR-associated proteins to insert whole genes into the genome, scientists report.
🔔 Subscribe for new episodes: https://www.youtube.com/@seankim?sub_confirmation=1▶️ Recommended for you: https://www.youtube.com/watch?v=xGlVx_6_A3oStephen…
A new study published in Nature has identified taurine, a common ingredient in energy drinks, as a nutrient that supports the survival and growth of leukemia stem cells in aggressive blood cancers.
Though taurine is known for its antioxidant and neuroprotective properties, the findings suggest it may play a harmful role in certain cancers.
The study’s authors caution that taurine supplements, including those in energy drinks, could influence disease progression in leukemia patients and recommend further research.
A new theory suggests that psychedelics promote empathy, insight, and psychological flexibility by making the brain’s right hemisphere temporarily dominant over the left.
