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A protein that has been widely studied owing to its association with neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) is also linked to medulloblastoma, a type of central nervous system cancer. Medulloblastoma is one of the most common and aggressive brain tumors in children, arising from undifferentiated cells during early neural development.

A study led by a group of Brazilian scientists has shown in vitro and in vivo that the gene VAPB is linked to cell proliferation in these tumors. An article on the study is published in the journal Scientific Reports.

The discovery points to a potential marker of severity and, after more research, a future therapeutic target. Medulloblastoma is currently treated with a combination of surgery to remove the tumor and radiation therapy and/or chemotherapy, both of which are aggressive and can cause long-lasting brain damage.

California sales of battery-electric vehicles made up over a third of BEV sales across the U.S. last year, with Tesla leading the charge.

Apple today released the first beta of an upcoming visionOS 1.1 update for developers, allowing developers to test new features ahead of the software seeing a public launch. This is the first beta version of ‌visionOS‌ software that Apple has made available since the headset launched last Friday.

The ‌visionOS‌ beta can be downloaded by going to the Settings app on the device and toggling on developer betas. A registered developer account is required, and Apple recommends making a backup before installing new software.

The trio used artificial intelligence to decode sections of the text, which appear to be a philosophical exploration of pleasure.

The University of Rochester’s Laboratory for Laser Energetics (LLE) has just thrown a spark into the fusion energy race. In a series of experiments, scientists at LLE pioneered a revolutionary “spark plug” for direct-drive inertial confinement fusion (ICF) methods. This development could be vital to unlocking the future of clean and abundant energy.

The LLE is home to the large OMEGA laser system. They conducted experiments that fired 28 kilojoules of laser energy at small capsules filled with deuterium and tritium fuel. The result? Capsules implode, creating a plasma hot enough to kickstart fusion reactions between the fuel nuclei.

Join us on Patreon! https://www.patreon.com/MichaelLustgartenPhDDiscount Links: Epigenetic, Telomere Testing: https://trudiagnostic.com/?irclickid=U-s3Ii2r7x…

A common practice of prescribing anticoagulants to people who have had unexplained strokes should stop, according to a study led by researchers at Columbia, Weill Cornell Medicine, and the University of Washington and published in JAMA.

Anticoagulants were thought to prevent additional strokes in people whose initial stroke has an unknown cause but who have a heart condition, atrial cardiopathy, that resembles atrial fibrillation, a common cause of stroke.

“We know these drugs work for people with atrial fibrillation, so we thought that they would probably work for people with atrial cardiopathy as well,” says Mitchell Elkind, MD, professor of neurology at the Vagelos College of Physicians and Surgeons and one of the study’s leaders. “That was the basis for the trial.”

The existence and physical properties of topological excitations in ferroelectrics, especially mobile topological boundaries in one dimension, are of profound interest. Notably, topological excitations emerging in association with the neutral–ionic (NI) phase transition are theoretically suggested to carry fractional charges and cause anomalous charge transport. In recent years, we experimentally demonstrated mobile topological excitations in a quasi-one-dimensional (1D) ferroelectric, tetrathiafulvalene-p-chloranil[TTF-CA; TTF (C6H4S4) and CA (C6Cl4O2)], which shows the NI transition, using NMR, NQR, and electrical resistivity measurements. Thermally activated topological excitations carry charges and spins in the NI crossover region and in the ionic phase with a dimer liquid.