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Scientists have developed a new gene-therapy technique by transforming human cells into mass producers of tiny nano-sized particles full of genetic material that has the potential to reverse disease processes.

Though the research was intended as a proof of concept, the experimental therapy slowed and prolonged survival in mice with gliomas, which constitute about 80 percent of in humans.

The technique takes advantage of exosomes, fluid-filled sacs that release as a way to communicate with other cells.

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After decades of research, here it is: the first promising evidence in humans, albeit imperfect and early, that a cocktail of three drugs is enough to reverse the epigenetic clock—a measure of someone’s biological age and health.

The results came as a surprise to even the research team, who originally designed the trial for something a little less dazzling: to look at human growth hormone’s effects on the thymus, the cradle of the body’s immune system that deteriorates with age.

“Maintained immune function is seen in centenarians,” and thymus function is linked to all-cause mortality, explained study author Dr. Gregory Fahy at Intervene Immune, based in Los Angeles, California. “So we were hoping to use a year of growth hormone to maintain thymus function in middle-aged men, right before the tissue’s functions take a nosedive,” he said.

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For the December edition of the Journal Club hosted by Dr. Oliver Medvedik, we are joined by Dr. Matthew O’ Connor (Oki) formerly of SENS Research Foundation and now the head researcher at Underdog Pharma, a spin-off biotech company that is developing research conducted at SENS into a hopefully viable solution for heart disease.

Dr. O’Connor will be giving a short presentation covering the story of 7-Ketocholesterol, a harmful byproduct of oxidized cholesterol that Underdog believes is a suitable target for therapeautic intervention to prevent the formation of artery plaques, the basis of atherosclerosis. Then, we will review the new paper that his team has published and follow it up with discussion and questions.

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SpaceX is launching yet another rocket this evening — its 13th this year. This Falcon 9 launch is set for liftoff sometime during a window that’ll last for just over an hour, and that opens at 7:10 PM EST (4:10 PM PST) and extends to 8:38 PM EST (5:38 PM PST). The launch will use a first-stage rocket booster that previously flew in May and July of this year, and it’ll include an attempted landing of that booster, as well as a try at recovering both halves of the fairing used to protect the spacecraft’s cargo as it ascends to space.

The cargo itself is a satellite built by Boeing that hosts two payloads for different clients, including Japanese pay TV broadcast service provider SKY Perfect JSAT, and a high-speed broadband connectivity satellite developed by Kratos called Kacific1. The Falcon 9 spacecraft will be looking to deliver these to orbit around half-an-hour after liftoff.

It’s definitely going to be worth watching the secondary mission elements of this one, as SpaceX has so far succeeded only in recovering one half of a fairing used during a mission with a single barge stationed in the ocean. This will see it try to catch both pieces, using two ships named “Ms. Tree” and “Ms. Chief” that have been retrofitted with a large net assembly specifically for the purpose.

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Yes, the simple act of juggling has recently been linked with better brain function. A new study reveals that learning to juggle may cause certain areas of your brain to grow.

The study found that volunteers who participated in a juggling exercise improved white matter in two areas of their brains involved in visual and motor activity.

‘We have demonstrated that there are changes in the white matter of the brain — the bundles of nerve fibres that connect different parts of the brain — as a result of learning an entirely new skill,’ explains Dr Heidi Johansen-Berg of the Department of Clinical Neurology, University of Oxford, who led the work.

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Less than 3 million Bitcoin (BTC) remain to be mined, with the process expected to take around 121 years. Some allege however, that Google’s quantum computer, Sycamore, could do it in “less than 2 seconds”. But is that really possible?

One computer to rule them all

Despite having the most difficult network to mine, Bitcoin (BTC) could have met its match in the face of the Google’s quantum processor, Sycamore. According to one medium post, the device has enough computational power to mine all the remaining BTC in less than two seconds.

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