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Blog – Page 8582

A new open access paper takes a look at tryptophan and the role that it plays in the dysfunction of the immune system in the context of the age-related changes that occur in the microbiome [1].

The microbiome

The gut microbiome is a complex ecosystem of bacteria, archaea, eukarya, and viruses that live inside of us, some beneficial and some harmful, the balance of which keeps us alive. Four microbial phyla, Firmicutes, Bacteroides, Proteobacteria, and Actinobacteria, make up 98% of the total population of the intestinal microbiome.

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Recently, the first attempt in the United States to use the gene editing tool CRISPR to combat cancer appears to have gone well, according to the initial results of a small human trial to determine safety for the approach.

Gene editing is a way to permanently change DNA in order to potentially cure a disease by attacking the root causes. CRISPR is a tool that can cut DNA at a specific spot, allowing genes to be removed or replaced or new genes to be inserted. CRISPR and other similar gene editing tools have long been used in the lab and are finally, after many years, starting to reach human trials for cancer and other diseases.

The approach involved doctors harvesting immune T cells from three cancer patients’ bloodstreams and modifying those cells with CRISPR to make them better able to detect and destroy cancer. Two of the patients have multiple myeloma, and the third has a sarcoma. Essentially, this therapy uses the body’s own immune cells to fight the disease rather than going with the traditional route of using drugs to disrupt the growth and spread of cancer.

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The world’s first fully electric commercial aircraft took its inaugural test flight on Tuesday, taking off from the Canadian city of Vancouver and offering hope that airlines may one day end their polluting emissions.

“This proves that commercial aviation in all-electric form can work,” said Roei Ganzarski, chief executive of Seattle-based engineering firm magniX.

The company designed the plane’s motor and worked in partnership with Harbour Air, which ferries half a million passengers a year between Vancouver, Whistler ski resort and nearby islands and coastal communities.

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Abstract: In the context of warped extra-dimensional models with all fields propagating in the bulk, we address the phenomenology of a bulk scalar Higgs boson, and calculate its production cross section at the LHC as well as its tree-level effects on mediating flavor changing neutral currents. We perform the calculations based on two different approaches. First, we compute our predictions analytically by considering all the degrees of freedom emerging from the dimensional reduction (the infinite tower of Kaluza Klein modes (KK)). In the second approach, we perform our calculations numerically by considering only the effects caused by the first few KK modes, present in the 4-dimensional effective theory. In the case of a Higgs leaking far from the brane, both approaches give the same predictions as the effects of the heavier KK modes decouple. However, as the Higgs boson is pushed towards the TeV brane, the two approaches seem to be equivalent only when one includes heavier and heavier degrees of freedom (which do not seem to decouple). To reconcile these results it is necessary to introduce a type of higher derivative operator which essentially encodes the effects of integrating out the heavy KK modes and dresses the brane Higgs so that it looks just like a bulk Higgs.

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Two entrepreneurs from Mexico have created vegan leather out of cactus leaves. The cruelty-free leather is called Desserto.

Adrián López Velarde and Marte Cázarez are said to be the first to create organic leather out of only nopal (prickly-pear) cactus. They don’t use toxic chemicals, phthalates, or PVC in their design.

The vegan leather is partially biodegradable. It’s flexible, breathable, and lasts for at least 10 years. The material feels like animal-based leather. Companies can use it in furniture, cars, leather accessories, and clothing.

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O.,o.

Acknowledges the fact that the Greys are cross-breeding with human beings in an attempt to re-vitalize the genetic structure of their species.

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