Lifeboat Foundation

3D bioprinting continues to diversify as more and more companies and research organizations join the field, each bringing their own take on the technology to the table. French collaborative platform 3D.fab has an intriguing approach towards bioprinting that involves a freeform robot capable of directly printing on a part of the body. In the video below, the BioAssemblyBot prints what appears to be a bandage directly on an arm:

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The ability to measure mutations in plasma cell-free DNA (cfDNA) has the potential to revolutionize cancer surveillance and treatment by enabling longitudinal monitoring not possible with solid tumor biopsies. However, obtaining sufficient quantities of cfDNA remains a challenge for assay development and clinical translation; consequently, large volumes of venous blood are typically required. Here, we test proof-of-concept for using smaller volumes via fingerstick collection. Matched venous and fingerstick blood were obtained from seven patients with metastatic breast cancer. Fingerstick blood was separated at point-of-care using a novel paper-based concept to isolate plasma centrifuge-free. Patient cfDNA was then analyzed with or without a new method for whole genome amplification via rolling-circle amplification (WG-RCA). We identified somatic mutations by targeted sequencing and compared the concordance of mutation detection from venous and amplified capillary samples by droplet-digital PCR. Patient mutations were detected with 100% concordance after WG-RCA, although in some samples, allele frequencies showed greater variation likely due to differential amplification or primer inaccessibility. These pilot findings provide physiological evidence that circulating tumor DNA is accessible by fingerstick and sustains presence/absence of mutation detection after whole-genome amplification. Further refinement may enable simpler and less-invasive methods for longitudinal or theranostic surveillance of metastatic cancer.

A tiny interplanetary traveler called MarCO-B caught a stunning image of Mars as it bid farewell to the Red Planet.

Researchers find an unlikely source for the next superfood.

It’s the largest drill NASA has ever sent to space.

NASA sent an $850 million lander to Mars. Insight will dig deep into the planet as the first of its kind to study the planet’s interior.

A new discovery brings us a step closer to an anti-aging workout.

As more countries appreciate the advantages, she hopes they will be willing to join the coalition of countries committed to reversing the decline in pollinators. Currently, there are only 24 countries in this “coalition of the willing”, mostly from Europe. Eventually, she hopes there will be enough support to multilateral environmental agreement on pollinators similar to the international convention on trade in endangered species. “I hope this week’s conference will be the first step to bringing a multilateral agreement into being because that’s what we need,” she says.

Urgent planting of wildflowers will attract pollinators and boost farmers’ food crops, expert to tell UN.

ISS Infested With Space Bugs!

The International Space Station is infested with mysterious space bugs that may be leaving astronauts at risk of “serious harm,” according to a new study.

Scientists discovered a thriving ecosystem of “infectious organisms” aboard the station which are similar to bugs found in hospitals on Earth.

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