Infectious disease
Protein mapping finds 69 potential treatments for COVID-19.
Many are FDA-approved drugs that could be repurposed.
NASA, one of SpaceX’s biggest customers, also prohibits its employees from using Zoom, said Stephanie Schierholz, a spokeswoman for the U.S. space agency.
The Federal Bureau of Investigation’s Boston office on Monday issued a warning about Zoom, telling users not to make meetings on the site public or share links widely after it received two reports of unidentified individuals invading school sessions, a phenomenon known as “zoombombing.”
Investigative news site The Intercept on Tuesday reported that Zoom video is not end-to-end encrypted between meeting participants, and that the company could view sessions.
Retired astronaut Chris Hadfield is spending lockdown searching for a better test for COVID-19, rewiring his stove, and talking to Euronews about what isolation means — and how to deal with it.
Dozens of other teams around the world have potential vaccines in development.
But the Pittsburgh research is the first study on a Covid-19 vaccine candidate to be published after critique from fellow scientists at outside institutions.
The scientists were able to act quickly because they had already laid the groundwork during earlier epidemics of coronaviruses: Sars in 2003 and Mers in 2014.
“These two viruses, which are closely related to[Covid-19], teach us that a particular protein, called a spike protein, is important for inducing immunity against the virus. We knew exactly where to fight this new virus,” said Andrea Gambotto, associate professor of surgery at the Pittsburgh School of Medicine.
Vaccine developed by US researchers is injected by 400 ‘microneedles’ stuck onto the skin like a plaster.
Can we build a better world with the lessons learned around this pandemic?
There is discussion that globalism will give way to community resilience and local digital manufacture, storage and transportation to provide abundant resources for normal and unanticipated needs.
#CommunityResilience #CommunityResourceCentres
We must pressure our leaders to take the long view in any coronavirus economic recovery package, even if this feels like a short-term emergency.
Cells will ramp up gene expression in response to physical forces alone, a new study finds. Gene activation, the first step of protein production, starts less than one millisecond after a cell is stretched—hundreds of times faster than chemical signals can travel, the researchers report.
The scientists tested forces that are biologically relevant—equivalent to those exerted on human cells by breathing, exercising or vocalizing. They report their findings in the journal Science Advances.
“We found that force can activate genes without intermediates, without enzymes or signaling molecules in the cytoplasm,” said University of Illinois mechanical science and engineering professor Ning Wang, who led the research. “We also discovered why some genes can be activated by force and some cannot.”
Spain death toll passes 10,000; Catalonia asks Spanish army for help; Thailand imposes national curfew.
Given the rapid development of virtual reality technology, we may very well be moving toward a time when we’re able to manage the brain’s memories.
Could we develop a similar capability? That may depend heavily upon a handful of ambitious attempts at brain-computer interfacing. But science is moving in baby steps with other tactics in both laboratory animals and humans.
Thus far, there have been some notable achievements in rodent experiments, that haven’t done so well with humans. We don’t have a beam that can go into your mind and give you 60 years worth of new experiences. Nevertheless, the emerging picture is that the physical basis of memory is understandable to the point that we should be able to intervene — both in producing and eliminating specific memories.
At MIT’s Center for Neural Circuit Genetics, for example, scientists have modified memories in mice using an optogenetic interface. This technology involves genetic modification of tissues, in this case within the brain, to express proteins that respond to light. Triggered by implants that deliver laser beams, brain cells can be triggered to be more or less active. In research that has been published in the prestigious journal Nature, the MIT team used the approach in specific brain circuits important to memory consolidation. The researchers were able to enhance the development of negative memories — for instance a shock given to an animal’s leg — and also to convert those negative memories into positive memories. The latter was achieved by letting male mice enjoy some time with females, while nerve cells that usually deliver the negative impulses associated with the former shock were stimulated through the optogenetic interface.
The U.S. passed 1,000 coronavirus deaths in a single day Wednesday, a daily death toll more than double lung cancer and the flu.